If you want to add a UIImageView to the center of the screen with width and height of 100 pixel, you need to set center x constraint and center y constraint to the superview from the UIImageView and width, height constraint to the UIIMageView. Here is the code. There is way to do this in storyboard but i have written in code because its understandable for this situation in documentation.
UIImageView *imageView = [[UIImageView alloc] initWithFrame:CGRectMake(0, 0, 100.0, 100.0);
imageView.self.translatesAutoresizingMaskIntoConstraints = NO;
[imageView addConstraint:[NSLayoutConstraint constraintWithItem:imageView attribute:NSLayoutAttributeWidth relatedBy:NSLayoutRelationEqual toItem:nil attribute:NSLayoutAttributeNotAnAttribute multiplier:1.0 constant:100.0]];
[imageView addConstraint:[NSLayoutConstraint constraintWithItem:imageView attribute:NSLayoutAttributeHeight relatedBy:NSLayoutRelationEqual toItem:nil attribute:NSLayoutAttributeNotAnAttribute multiplier:1.0 constant:100.0]];
[superview addConstraint:[NSLayoutConstraint constraintWithItem:imageView attribute:NSLayoutAttributeCenterX relatedBy:NSLayoutRelationEqual toItem:superview attribute:NSLayoutAttributeCenterX multiplier:1.0 constant:0]];
[superview addConstraint:[NSLayoutConstraint constraintWithItem:imageView attribute:NSLayoutAttributeCenterX relatedBy:NSLayoutRelationEqual toItem:superview attribute:NSLayoutAttributeCenterX multiplier:1.0 constant:0]];