The function np.loadtxt can be used to read csv-like files:
# File:
#    # Col_1 Col_2
#    1, 1
#    2, 4
#    3, 9
np.loadtxt('/path/to/dir/csvlike.txt', delimiter=',', comments='#')
# Output:
# array([[ 1.,  1.],
#        [ 2.,  4.],
#        [ 3.,  9.]])
The same file could be read ...