Supposing you have setup a django project, and the settings file is in an app named main, this is how you initialize your code
import os, sys
# Setup environ
sys.path.append(os.getcwd())
os.environ.setdefault("DJANGO_SETTINGS_MODULE", "main.settings")
# Setup django
import django
django.setup()
# rest of your imports go here
from main.models import MyModel
# normal python code that makes use of Django models go here
for obj in MyModel.objects.all():
print obj
The above can be executed as
python main/cli.py