Static method:
Dim parseMethod = GetType(Integer).GetMethod("Parse",{GetType(String)})
Dim result = DirectCast(parseMethod.Invoke(Nothing,{"123"}), Integer)
Instance method:
Dim instance = "hello".ToUpper
Dim method = Gettype(String).GetMethod("ToUpper",{})
Dim result = method.Invoke(instance,{})
Console.WriteLine(result) 'HELLO