AMD is a processor manufacturer that had licensed the design of the 80386 from Intel to produce compatible - but competing - versions. They made internal changes to the design to improve throughput or other enhancements to the design, while still being able to execute the same programs.
To one-up Intel, they came up with 64-bit extensions to the Intel 32-bit design and produced the first 64-bit chip that could still run 32-bit x86 code. Intel ended up following AMD's design in their versions of the 64-bit architecture.
The 64-bit design made a number of changes to the register set, while still being backward compatible:
R prefix: RAX, RBX, RCX, RDX, RSI, RDI, RBP, and RSP.
Again, the bottom halves of these registers were the same
E-prefix registers as before, and the top halves couldn't be independently accessed.
R8, R9, R10, R11, R12, R13, R14, and R15.
R8D through R15D (D for DWORD as usual).W to the register name: R8W through R15W.AL, BL, CL, and DL;SIL, DIL, BPL, and SPL;R8B through R15B.AH, BH, CH, and DH are inaccessible in instructions that use a REX prefix (for 64bit operand size, or to access R8-R15, or to access SIL, DIL, BPL, or SPL). With a REX prefix, the machine-code bit-pattern that used to mean AH instead means SPL, and so on. See Table 3-1 of Intel's instruction reference manual (volume 2).Writing to a 32-bit register always zeros the upper 32 bits of the full-width register, unlike writing to an 8 or 16-bit register (which merges with the old value, which is an extra dependency for out-of-order execution).