You can open several content managers at the same time:
with open(input_path) as input_file, open(output_path, 'w') as output_file:
# do something with both files.
# e.g. copy the contents of input_file into output_file
for line in input_file:
output_file.write(line + '\n')
It has the same effect as nesting context managers:
with open(input_path) as input_file:
with open(output_path, 'w') as output_file:
for line in input_file:
output_file.write(line + '\n')