Example
- Open the Settings or Preferences dialog:
- On Windows or Linux, select
File > Settings from the main menu.
- On Mac OSX, select
Android Studio > Preferences from the main menu.
- Navigate to
Build, Execution, Deployment > Compiler.
- In the text field next to Command-line Options, enter your command-line options.
- Click OK to save and exit.

The top option is Instant run. Check/uncheck that box.
Documentation